For physicians in nephrology & critical care

Citrate anticoagulation, organized by evidence, not by habit.

Protocols, current literature, and practical management of regional citrate anticoagulation for continuous and intermittent renal replacement therapy — with a clear distinction between established standard use and off-label application.

Protocols by modality

Standard modality

CVVHD

Continuous veno-venous hemodialysis. Citrate has become the anticoagulant of choice at most centers.

e.g. Multifiltrate, Prismaflex

Off-label

Genius system

An intermittent modality. Citrate anticoagulation is off-label here, and protocols vary more between centers.

Genius (Fresenius)

Latest literature

This section will be populated automatically from PubMed with new publications on citrate anticoagulation in CRRT. Placeholder for the next build stage.

The content on this site is for professional orientation only and does not replace individual clinical judgment. Protocols must be reviewed and approved by the respective center. Off-label uses are marked accordingly.